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Mitochondria are the metabolic hubs of the cell, transforming nutrients into ATP—the molecular energy currency that powers nearly every biological process. Dysfunction of these organelles is increasingly implicated in a wide range of diseases, including neurodegeneration, cancer, diabetes, myopathies, and aging. Despite their central role, much remains unknown about mitochondrial function across diverse physiological contexts.

Mitochondria are highly dynamic, constantly undergoing membrane fusion and fission. Their morphology is closely tied to their function and to the maintenance of cellular homeostasis. Yet quantifying mitochondrial shape and behavior from imaging data remains a significant challenge.

MitoGraphica offers expert image analysis and consultation to both academia and industry, streamlining the process of transforming mitochondrial images into quantitative data that drive biological insight.

If you have images of mitochondria—or intend to generate some—MitoGraphica can help you:

• Receive tailored expert consultation

• Analyze images, providing standard readouts of mitochondrial structure and function, including:

  • Aspect ratio

  • Circularity

  • Count/number

  • Area

  • Colocalization

  • Membrane potential (ΔΨm)

  • Mitophagy

  • mtDNA copy number

  • Reactive oxygen species (ROS)

  • Fusion/fission rates

• Generate graphs and figures suitable for publication, regulatory filings (e.g., IND-enabling studies), or internal reporting

• Design and interpret experiments involving mitochondria, including image analysis, respirometry, and related techniques